Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy

Avian influenza A viruses generally do not replicate efficiently in human cells, but substitution of glutamic acid (Glu, E) for lysine (Lys, K) at residue 627 of avian influenza virus polymerase basic protein 2 (PB2) can serve to overcome host restriction and facilitate human infectivity. Although P...

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Detalles Bibliográficos
Autores principales: Kuo, Shu-Ming, Chen, Chi-Jene, Chang, Shih-Cheng, Liu, Tzu-Jou, Chen, Yi-Hsiang, Huang, Sheng-Yu, Shih, Shin-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472184/
https://www.ncbi.nlm.nih.gov/pubmed/28611246
http://dx.doi.org/10.1128/mBio.00481-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472184/
https://www.ncbi.nlm.nih.gov/pubmed/28611246
http://dx.doi.org/10.1128/mBio.00481-17

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