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Translational Control of the SigR-Directed Oxidative Stress Response in Streptomyces via IF3-Mediated Repression of a Noncanonical GTC Start Codon

The major oxidative stress response in Streptomyces is controlled by the sigma factor SigR and its cognate antisigma factor RsrA, and SigR activity is tightly controlled through multiple mechanisms at both the transcriptional and posttranslational levels. Here we show that sigR has a highly unusual...

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Detalles Bibliográficos
Autores principales: Feeney, Morgan A., Chandra, Govind, Findlay, Kim C., Paget, Mark S. B., Buttner, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472188/
https://www.ncbi.nlm.nih.gov/pubmed/28611250
http://dx.doi.org/10.1128/mBio.00815-17