Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins

Finasteride (FIN) is a Class II candidate of the Biopharmaceutics Classification System (BCS). The lipophilic cavity of cyclodextrins (CyDs) enables it to construct a non-covalent inclusion complex with different insoluble drugs. Only β-cyclodextrin (β-CyD) and hydroxypropyl-β-CyD (HP-β-CyD) have be...

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Detalles Bibliográficos
Autores principales: Mady, Fatma M, Farghaly Aly, Usama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472428/
https://www.ncbi.nlm.nih.gov/pubmed/28652706
http://dx.doi.org/10.2147/DDDT.S135084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472428/
https://www.ncbi.nlm.nih.gov/pubmed/28652706
http://dx.doi.org/10.2147/DDDT.S135084

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