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Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins
Finasteride (FIN) is a Class II candidate of the Biopharmaceutics Classification System (BCS). The lipophilic cavity of cyclodextrins (CyDs) enables it to construct a non-covalent inclusion complex with different insoluble drugs. Only β-cyclodextrin (β-CyD) and hydroxypropyl-β-CyD (HP-β-CyD) have be...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472428/ https://www.ncbi.nlm.nih.gov/pubmed/28652706 http://dx.doi.org/10.2147/DDDT.S135084 |