Substrate transport and anion permeation proceed through distinct pathways in glutamate transporters

Advances in structure-function analyses and computational biology have enabled a deeper understanding of how excitatory amino acid transporters (EAATs) mediate chloride permeation and substrate transport. However, the mechanism of structural coupling between these functions remains to be established...

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Detalles Bibliográficos
Autores principales: Cheng, Mary Hongying, Torres-Salazar, Delany, Gonzalez-Suarez, Aneysis D, Amara, Susan G, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472439/
https://www.ncbi.nlm.nih.gov/pubmed/28569666
http://dx.doi.org/10.7554/eLife.25850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472439/
https://www.ncbi.nlm.nih.gov/pubmed/28569666
http://dx.doi.org/10.7554/eLife.25850

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