The Nogo-B receptor promotes Ras plasma membrane localization and activation

The localization of prenylated Ras at the plasma membrane promotes activation of Ras by receptor tyrosine kinases and stimulates oncogenic signaling by mutant Ras. The Nogo-B receptor (NgBR) is a transmembrane receptor that contains a conserved hydrophobic pocket. Here, we demonstrate that the NgBR...

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Detalles Bibliográficos
Autores principales: Zhao, Baofeng, Hu, Wenquan, Kumar, Suresh, Gonyo, Patrick, Rana, Ujala, Liu, Zhong, Wang, Bei, Duong, William Q., Yang, Zhe, Williams, Carol L., Miao, Qing R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472485/
https://www.ncbi.nlm.nih.gov/pubmed/28068323
http://dx.doi.org/10.1038/onc.2016.484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472485/
https://www.ncbi.nlm.nih.gov/pubmed/28068323
http://dx.doi.org/10.1038/onc.2016.484

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