Improved Gene Delivery to Adult Mouse Spinal Cord Through the Use of Engineered Hybrid Adeno-Associated Viral serotypes

Adeno-associated viral (AAV) vectors are often used in gene therapy for neurological disorders because of its safety profile and promising results in clinical trials. One challenge to AAV gene therapy is effective transduction of large numbers of the appropriate cell type, which can be overcome by m...

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Detalles Bibliográficos
Autores principales: Siu, Jason J., Queen, Nicholas J., Huang, Wei, Yin, Feng Qin, Liu, Xianglan, McTigue, Dana M., Cao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472488/
https://www.ncbi.nlm.nih.gov/pubmed/28440798
http://dx.doi.org/10.1038/gt.2017.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472488/
https://www.ncbi.nlm.nih.gov/pubmed/28440798
http://dx.doi.org/10.1038/gt.2017.27

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