Biodistribution and residence time of adenovector serotype 5 in normal and immunodeficient mice and rats detected with bioluminescent imaging

As concerns increase about adenovirus type 5 (Ad5) being a safe gene transfer vector, it is important to evaluate its distribution, residence time, and possible toxicity in immunodeficient populations. To characterize the potential risk associated with different Ad5 vector delivery modes, we used im...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Zhou, Shuya, Fan, Changfa, Huang, Weijin, Li, Qianqian, Liu, Susu, Wu, Xi, Li, Baowen, Wang, Youchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472566/
https://www.ncbi.nlm.nih.gov/pubmed/28620164
http://dx.doi.org/10.1038/s41598-017-03852-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472566/
https://www.ncbi.nlm.nih.gov/pubmed/28620164
http://dx.doi.org/10.1038/s41598-017-03852-0

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