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Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus

Pemphigus is an autoimmune blistering skin disease caused primarily by autoantibodies against desmoglein (Dsg)1 and 3. Here, we characterized the mechanisms engaged by pemphigus IgG from patients with different clinical phenotypes and autoantibody profiles. All pemphigus vulgaris (PV) and pemphigus...

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Detalles Bibliográficos
Autores principales: Walter, Elias, Vielmuth, Franziska, Rotkopf, Lukas, Sárdy, Miklós, Horváth, Orsolya N., Goebeler, Matthias, Schmidt, Enno, Eming, Rüdiger, Hertl, Michael, Spindler, Volker, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472593/
https://www.ncbi.nlm.nih.gov/pubmed/28620161
http://dx.doi.org/10.1038/s41598-017-03697-7