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Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress

Based on the oxidative stress theory, aging derives from the accumulation of oxidized proteins induced by reactive oxygen species (ROS) in the cytoplasm. Hydrogen peroxide (H(2)O(2)) elicits ROS that induces skin aging through oxidation of proteins, forming disulfide bridges with cysteine or methion...

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Detalles Bibliográficos
Autores principales: Wu, Ching-Ying, Hsu, Wen-Li, Tsai, Ming-Hsien, Liang, Jui-Lin, Lu, Jian-He, Yen, Chia-Jung, Yu, Hsin-Su, Noda, Mami, Lu, Chi-Yu, Chen, Chu-Huang, Yan, Shian-Jang, Yoshioka, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472599/
https://www.ncbi.nlm.nih.gov/pubmed/28620198
http://dx.doi.org/10.1038/s41598-017-03513-2