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Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress
Based on the oxidative stress theory, aging derives from the accumulation of oxidized proteins induced by reactive oxygen species (ROS) in the cytoplasm. Hydrogen peroxide (H(2)O(2)) elicits ROS that induces skin aging through oxidation of proteins, forming disulfide bridges with cysteine or methion...
Autores principales: | Wu, Ching-Ying, Hsu, Wen-Li, Tsai, Ming-Hsien, Liang, Jui-Lin, Lu, Jian-He, Yen, Chia-Jung, Yu, Hsin-Su, Noda, Mami, Lu, Chi-Yu, Chen, Chu-Huang, Yan, Shian-Jang, Yoshioka, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472599/ https://www.ncbi.nlm.nih.gov/pubmed/28620198 http://dx.doi.org/10.1038/s41598-017-03513-2 |
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