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Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion

Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults with a 5-year survival rate of 5% despite intensive research efforts. The poor prognosis is due, in part, to aggressive invasion into the surrounding brain parenchyma. Invasion is a complex process mediated by cell-intr...

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Detalles Bibliográficos
Autores principales: Roos, Alison, Ding, Zonghui, Loftus, Joseph C., Tran, Nhan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472661/
https://www.ncbi.nlm.nih.gov/pubmed/28670569
http://dx.doi.org/10.3389/fonc.2017.00120