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Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion
Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults with a 5-year survival rate of 5% despite intensive research efforts. The poor prognosis is due, in part, to aggressive invasion into the surrounding brain parenchyma. Invasion is a complex process mediated by cell-intr...
Autores principales: | Roos, Alison, Ding, Zonghui, Loftus, Joseph C., Tran, Nhan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472661/ https://www.ncbi.nlm.nih.gov/pubmed/28670569 http://dx.doi.org/10.3389/fonc.2017.00120 |
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