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N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca(2+) Mobilization

Resistance of cancer cells to chemotherapy remains a significant problem in oncology. Mechanisms regulating programmed cell death, including apoptosis, autophagy or necrosis, in the treatment of cancers have been extensively investigated over the last few decades. Autophagy is now emerging as an imp...

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Detalles Bibliográficos
Autores principales: Law, Betty Y. K., Mok, Simon W. F., Chen, Juan, Michelangeli, Francesco, Jiang, Zhi-Hong, Han, Yu, Qu, Yuan Q., Qiu, Alena C. L., Xu, Su-Wei, Xue, Wei-Wei, Yao, Xiao-Jun, Gao, Jia Y., Javed, Masood-ul-Hassan, Coghi, Paolo, Liu, Liang, Wong, Vincent K. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472688/
https://www.ncbi.nlm.nih.gov/pubmed/28670281
http://dx.doi.org/10.3389/fphar.2017.00388