Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes

Functional consequences for most inflammatory disease-associated loci are incompletely defined, including in the LACC1 (C13orf31) region. Here we show that human peripheral and intestinal myeloid-derived cells express laccase domain-containing 1 (LACC1); LACC1 is expressed in both the cytoplasm and...

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Detalles Bibliográficos
Autores principales: Lahiri, Amit, Hedl, Matija, Yan, Jie, Abraham, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472760/
https://www.ncbi.nlm.nih.gov/pubmed/28593945
http://dx.doi.org/10.1038/ncomms15614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472760/
https://www.ncbi.nlm.nih.gov/pubmed/28593945
http://dx.doi.org/10.1038/ncomms15614

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