Cargando…
Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes
Functional consequences for most inflammatory disease-associated loci are incompletely defined, including in the LACC1 (C13orf31) region. Here we show that human peripheral and intestinal myeloid-derived cells express laccase domain-containing 1 (LACC1); LACC1 is expressed in both the cytoplasm and...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472760/ https://www.ncbi.nlm.nih.gov/pubmed/28593945 http://dx.doi.org/10.1038/ncomms15614 |