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Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

Thymocyte-expressed, positive selection-associated 1 (Tespa1) is important in T cell receptor (TCR)-driven thymocyte development. Downstream of the TCR, Tespa1 is a crucial component of the linker for activation of T cells (LAT) signalosome, facilitating calcium signalling and subsequent MAPK activa...

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Detalles Bibliográficos
Autores principales: Liang, Jingjing, Lyu, Jun, Zhao, Meng, Li, Dan, Zheng, Mingzhu, Fang, Yan, Zhao, Fangzhu, Lou, Jun, Guo, Chuansheng, Wang, Lie, Wang, Di, Liu, Wanli, Lu, Linrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472764/
https://www.ncbi.nlm.nih.gov/pubmed/28598420
http://dx.doi.org/10.1038/ncomms15732