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INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers

ATP-dependent chromatin remodellers modulate nucleosome dynamics by mobilizing or disassembling nucleosomes, as well as altering nucleosome composition. These chromatin remodellers generally function by translocating along nucleosomal DNA at the H3–H4 interface of nucleosomes. Here we show that, unl...

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Detalles Bibliográficos
Autores principales: Brahma, Sandipan, Udugama, Maheshi I., Kim, Jongseong, Hada, Arjan, Bhardwaj, Saurabh K., Hailu, Solomon G., Lee, Tae-Hee, Bartholomew, Blaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472786/
https://www.ncbi.nlm.nih.gov/pubmed/28604691
http://dx.doi.org/10.1038/ncomms15616