Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

Proper segregation of chromosomes depends on a functional spindle assembly checkpoint (SAC) and requires kinetochore localization of the Bub1 and Mad1/Mad2 checkpoint proteins. Several aspects of Mad1/Mad2 kinetochore recruitment in human cells are unclear and in particular the underlying direct int...

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Detalles Bibliográficos
Autores principales: Zhang, Gang, Kruse, Thomas, López-Méndez, Blanca, Sylvestersen, Kathrine Beck, Garvanska, Dimitriya H., Schopper, Simone, Nielsen, Michael Lund, Nilsson, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472792/
https://www.ncbi.nlm.nih.gov/pubmed/28604727
http://dx.doi.org/10.1038/ncomms15822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472792/
https://www.ncbi.nlm.nih.gov/pubmed/28604727
http://dx.doi.org/10.1038/ncomms15822

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