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Identification of the elementary structural units of the DNA damage response

Histone H2AX phosphorylation is an early signalling event triggered by DNA double-strand breaks (DSBs). To elucidate the elementary units of phospho-H2AX-labelled chromatin, we integrate super-resolution microscopy of phospho-H2AX during DNA repair in human cells with genome-wide sequencing analyses...

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Detalles Bibliográficos
Autores principales: Natale, Francesco, Rapp, Alexander, Yu, Wei, Maiser, Andreas, Harz, Hartmann, Scholl, Annina, Grulich, Stephan, Anton, Tobias, Hörl, David, Chen, Wei, Durante, Marco, Taucher-Scholz, Gisela, Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472794/
https://www.ncbi.nlm.nih.gov/pubmed/28604675
http://dx.doi.org/10.1038/ncomms15760