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In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer

BACKGROUND: Hypoxia is a characteristic of breast tumours indicating poor prognosis. Based on the assumption that those genes which are up-regulated under hypoxia in cell-lines are expected to be predictors of poor prognosis in clinical data, many signatures of poor prognosis were identified. Howeve...

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Detalles Bibliográficos
Autores principales: Abu-Jamous, Basel, Buffa, Francesca M., Harris, Adrian L., Nandi, Asoke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472949/
https://www.ncbi.nlm.nih.gov/pubmed/28619028
http://dx.doi.org/10.1186/s12943-017-0673-0