Cargando…

Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy

[Image: see text] Autophagy is an essential pathway by which cellular and foreign material are degraded and recycled in eukaryotic cells. Induction of autophagy is a promising approach for treating diverse human diseases, including neurodegenerative disorders and infectious diseases. Here, we report...

Descripción completa

Detalles Bibliográficos
Autores principales: Peraro, Leila, Zou, Zhongju, Makwana, Kamlesh M., Cummings, Ashleigh E., Ball, Haydn L., Yu, Hongtao, Lin, Yu-Shan, Levine, Beth, Kritzer, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473019/
https://www.ncbi.nlm.nih.gov/pubmed/28414223
http://dx.doi.org/10.1021/jacs.7b01698