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Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins

A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane protein which is essential for embryonic development through activation of Notch proteins. ADAM10 regulates over 40 other transmembrane proteins and acts as a ‘molecular scissor’ by removing their extracellular r...

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Detalles Bibliográficos
Autores principales: Matthews, Alexandra L., Szyroka, Justyna, Collier, Richard, Noy, Peter J., Tomlinson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473022/
https://www.ncbi.nlm.nih.gov/pubmed/28620033
http://dx.doi.org/10.1042/BST20160290