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Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins
A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane protein which is essential for embryonic development through activation of Notch proteins. ADAM10 regulates over 40 other transmembrane proteins and acts as a ‘molecular scissor’ by removing their extracellular r...
Autores principales: | Matthews, Alexandra L., Szyroka, Justyna, Collier, Richard, Noy, Peter J., Tomlinson, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473022/ https://www.ncbi.nlm.nih.gov/pubmed/28620033 http://dx.doi.org/10.1042/BST20160290 |
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