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Superior long-term synaptic memory induced by combining dual pharmacological activation of PKA and ERK with an enhanced training protocol

Developing treatment strategies to enhance memory is an important goal of neuroscience research. Activation of multiple biochemical signaling cascades, such as the protein kinase A (PKA) and extracellular signal-regulated kinase (ERK) pathways, is necessary to induce long-term synaptic facilitation...

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Detalles Bibliográficos
Autores principales: Liu, Rong-Yu, Neveu, Curtis, Smolen, Paul, Cleary, Leonard J., Byrne, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473109/
https://www.ncbi.nlm.nih.gov/pubmed/28620076
http://dx.doi.org/10.1101/lm.044834.116