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MicroRNA-27b functions as a new inhibitor of ovarian cancer-mediated vasculogenic mimicry through suppression of VE-cadherin expression

Aggressive cancer cells gain robust tumor vascular mimicry (VM) capability that promotes tumor growth and metastasis. VE-cadherin is aberrantly overexpressed in vasculogenic cancer cells and regarded as a master gene of tumor VM. Although microRNAs (miRNAs) play an important role in modulating tumor...

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Detalles Bibliográficos
Autores principales: Liu, Wenming, Lv, Chunping, Zhang, Bin, Zhou, Quansheng, Cao, Zhifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473136/
https://www.ncbi.nlm.nih.gov/pubmed/28396577
http://dx.doi.org/10.1261/rna.059592.116