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Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA

Three families of nucleic acid-dependent ATPases (DEAH/RHA, Ski2-like, and NS3/NPH-II), termed the DExH ATPases, are thought to execute myriad functions by processive, ATP-dependent, 3′ to 5′ translocation along single-stranded nucleic acid. While the mechanism of translocation of the viral NS3/NPH-...

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Detalles Bibliográficos
Autores principales: He, Yangzi, Staley, Jonathan P., Andersen, Gregers Rom, Nielsen, Klaus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473145/
https://www.ncbi.nlm.nih.gov/pubmed/28416566
http://dx.doi.org/10.1261/rna.060954.117