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RNA-guided transcriptional activation via CRISPR/dCas9 mimics overexpression phenotypes in Arabidopsis

Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR associated protein 9 (Cas9) system allows effective gene modification through RNA-guided DNA targeting. The Cas9 has undergone a series of functional alterations from the original active endonuclease to partially or co...

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Detalles Bibliográficos
Autores principales: Park, Jong-Jin, Dempewolf, Emma, Zhang, Wenzheng, Wang, Zeng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473554/
https://www.ncbi.nlm.nih.gov/pubmed/28622347
http://dx.doi.org/10.1371/journal.pone.0179410