Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA

Cellular homeostasis of the minor spliceosome is regulated by a negative feed-back loop that targets U11-48K and U11/U12-65K mRNAs encoding essential components of the U12-type intron-specific U11/U12 di-snRNP. This involves interaction of the U11 snRNP with an evolutionarily conserved splicing enha...

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Detalles Bibliográficos
Autores principales: Verbeeren, Jens, Verma, Bhupendra, Niemelä, Elina H., Yap, Karen, Makeyev, Eugene V., Frilander, Mikko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473595/
https://www.ncbi.nlm.nih.gov/pubmed/28549066
http://dx.doi.org/10.1371/journal.pgen.1006824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473595/
https://www.ncbi.nlm.nih.gov/pubmed/28549066
http://dx.doi.org/10.1371/journal.pgen.1006824

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