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Biodegradable and biocompatible cationic polymer delivering microRNA-221/222 promotes nerve regeneration after sciatic nerve crush

MicroRNA (miRNA) has great potential to treat a wide range of illnesses by regulating the expression of eukaryotic genes. Biomaterials with high transfection efficiency and low toxicity are needed to deliver miRNA to target cells. In this study, a biodegradable and biocompatible cationic polymer (PD...

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Detalles Bibliográficos
Autores principales: Song, Jialin, Li, Xueyang, Li, Yingli, Che, Junyi, Li, Xiaoming, Zhao, Xiaotian, Chen, Yinghui, Zheng, Xianyou, Yuan, Weien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473607/
https://www.ncbi.nlm.nih.gov/pubmed/28652727
http://dx.doi.org/10.2147/IJN.S132190