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Autophagy controls centrosome number by degrading Cep63

Centrosome number is associated with the chromosome segregation and genomic stability. The ubiquitin–proteasome system is considered to be the main regulator of centrosome number. However, here we show that autophagy also regulates the number of centrosomes. Autophagy-deficient cells carry extra cen...

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Detalles Bibliográficos
Autores principales: Watanabe, Yuichiro, Honda, Shinya, Konishi, Akimitsu, Arakawa, Satoko, Murohashi, Michiko, Yamaguchi, Hirofumi, Torii, Satoru, Tanabe, Minoru, Tanaka, Shinji, Warabi, Eiji, Shimizu, Shigeomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473638/
https://www.ncbi.nlm.nih.gov/pubmed/27869116
http://dx.doi.org/10.1038/ncomms13508