In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

Several CRISPR-Cas9 orthologues have been used for genome editing. Here, we present the smallest Cas9 orthologue characterized to date, derived from Campylobacter jejuni (CjCas9), for efficient genome editing in vivo. After determining protospacer-adjacent motif (PAM) sequences and optimizing single...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eunji, Koo, Taeyoung, Park, Sung Wook, Kim, Daesik, Kim, Kyoungmi, Cho, Hee-Yeon, Song, Dong Woo, Lee, Kyu Jun, Jung, Min Hee, Kim, Seokjoong, Kim, Jin Hyoung, Kim, Jeong Hun, Kim, Jin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473640/
https://www.ncbi.nlm.nih.gov/pubmed/28220790
http://dx.doi.org/10.1038/ncomms14500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473640/
https://www.ncbi.nlm.nih.gov/pubmed/28220790
http://dx.doi.org/10.1038/ncomms14500

Ejemplares similares