Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice

Host genetic variation is known to contribute to differential pathogenesis following infection. Mouse models allow direct assessment of host genetic factors responsible for susceptibility to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV). Based on an assessment of early stage lines from th...

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Detalles Bibliográficos
Autores principales: Gralinski, Lisa E., Menachery, Vineet D., Morgan, Andrew P., Totura, Allison L., Beall, Anne, Kocher, Jacob, Plante, Jessica, Harrison-Shostak, D. Corinne, Schäfer, Alexandra, Pardo-Manuel de Villena, Fernando, Ferris, Martin T., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Multiparental Populations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473747/
https://www.ncbi.nlm.nih.gov/pubmed/28592648
http://dx.doi.org/10.1534/g3.117.041434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473747/
https://www.ncbi.nlm.nih.gov/pubmed/28592648
http://dx.doi.org/10.1534/g3.117.041434

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