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Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross

The oligoadenylate-synthetase (Oas) gene locus provides innate immune resistance to virus infection. In mouse models, variation in the Oas1b gene influences host susceptibility to flavivirus infection. However, the impact of Oas variation on overall innate immune programming and global gene expressi...

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Detalles Bibliográficos
Autores principales: Green, Richard, Wilkins, Courtney, Thomas, Sunil, Sekine, Aimee, Hendrick, Duncan M., Voss, Kathleen, Ireton, Renee C., Mooney, Michael, Go, Jennifer T., Choonoo, Gabrielle, Jeng, Sophia, de Villena, Fernando Pardo-Manuel, Ferris, Martin T., McWeeney, Shannon, Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473748/
https://www.ncbi.nlm.nih.gov/pubmed/28592649
http://dx.doi.org/10.1534/g3.117.041624