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SLC25 Family Member Genetic Interactions Identify a Role for HEM25 in Yeast Electron Transport Chain Stability

The SLC25 family member SLC25A38 (Hem25 in yeast) was recently identified as a mitochondrial glycine transporter that provides substrate to initiate heme/hemoglobin synthesis. Mutations in the human SLC25A38 gene cause congenital sideroblastic anemia. The full extent to which SLC25 family members co...

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Detalles Bibliográficos
Autores principales: Dufay, J. Noelia, Fernández-Murray, J. Pedro, McMaster, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473764/
https://www.ncbi.nlm.nih.gov/pubmed/28404662
http://dx.doi.org/10.1534/g3.117.041194