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TCRP1 transcriptionally regulated by c-Myc confers cancer chemoresistance in tongue and lung cancer

Previously, we cloned a new gene termed ‘tongue cancer resistance-associated protein 1’ (TCRP1), which modulates tumorigenesis, enhances cisplatin (cDDP) resistance in cancers, and may be a potential target for reversing drug resistance. However, the mechanisms for regulating TCRP1 expression remain...

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Detalles Bibliográficos
Autores principales: Jia, Xiaoting, Zhang, Zhijie, Luo, Kai, Zheng, Guopei, Lu, Minying, Song, Ying, Liu, Hao, Qiu, Huisi, He, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473818/
https://www.ncbi.nlm.nih.gov/pubmed/28623290
http://dx.doi.org/10.1038/s41598-017-03763-0