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Fibronectin promotes directional persistence in fibroblast migration through interactions with both its cell-binding and heparin-binding domains
The precise mechanisms through which insoluble, cell-adhesive ligands induce and regulate directional cell migration remain obscure. We recently demonstrated that elevated surface density of physically adsorbed plasma fibronectin (FN) promotes high directional persistence in fibroblast migration. Wh...
Autores principales: | Missirlis, Dimitris, Haraszti, Tamás, Kessler, Horst, Spatz, Joachim P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473823/ https://www.ncbi.nlm.nih.gov/pubmed/28623309 http://dx.doi.org/10.1038/s41598-017-03701-0 |
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