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Dosage compensation in the process of inactivation/reactivation during both germ cell development and early embryogenesis in mouse

Ohno proposed that dosage compensation in mammals evolved as a two-step mechanism involving X-inactivation and X-upregulation. While X-inactivation is well characterized, it remains to further analysis whether upregulation of the single activated X chromosome in mammals occurs. We obtained RNA-seq d...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyong, Hu, Zhiqiang, Yu, Xuelin, Zhang, Chen, Ma, Binbin, He, Lin, Wei, Chaochun, Wu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473838/
https://www.ncbi.nlm.nih.gov/pubmed/28623283
http://dx.doi.org/10.1038/s41598-017-03829-z