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Dosage compensation in the process of inactivation/reactivation during both germ cell development and early embryogenesis in mouse
Ohno proposed that dosage compensation in mammals evolved as a two-step mechanism involving X-inactivation and X-upregulation. While X-inactivation is well characterized, it remains to further analysis whether upregulation of the single activated X chromosome in mammals occurs. We obtained RNA-seq d...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473838/ https://www.ncbi.nlm.nih.gov/pubmed/28623283 http://dx.doi.org/10.1038/s41598-017-03829-z |