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Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells

Non-alcoholic fatty liver disease (NAFLD) is a dominant cause of chronic liver disease, but the exact mechanism of progression from simple steatosis to nonalcoholic steatohepatitis (NASH) remains unknown. Here, we investigated the role of exosomes in NAFLD progression. Exosomes were isolated from a...

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Detalles Bibliográficos
Autores principales: Lee, Young-Sun, Kim, So Yeon, Ko, Eunjung, Lee, Jun-Hee, Yi, Hyon-Seung, Yoo, Yang Jae, Je, Jihye, Suh, Sang Jun, Jung, Young Kul, Kim, Ji Hoon, Seo, Yeon Seok, Yim, Hyung Joon, Jeong, Won-Il, Yeon, Jong Eun, Um, Soon Ho, Byun, Kwan Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473841/
https://www.ncbi.nlm.nih.gov/pubmed/28623272
http://dx.doi.org/10.1038/s41598-017-03389-2