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The role of PTEN - HCV core interaction in hepatitis C virus replication

Hepatitis C virus (HCV) infection leads to severe liver diseases including hepatocellular carcinoma (HCC). Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a tumour suppressor, is frequently mutated or deleted in HCC tumors. PTEN has previously been demonstrated to inhibit HCV secreti...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Li, Zhubing, Mellor, Paul, Zhou, Yan, Anderson, Deborah H., Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473856/
https://www.ncbi.nlm.nih.gov/pubmed/28623358
http://dx.doi.org/10.1038/s41598-017-03052-w