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Crystal structure of the DNA-binding domain of Myelin-gene Regulatory Factor

Myelin-gene Regulatory Factor (MyRF) is one of the master transcription factors controlling myelin formation and development in oligodendrocytes which is crucial for the powerful brain functions. The N-terminal of MyRF, which contains a proline-rich region and a DNA binding domain (DBD), is auto-cle...

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Detalles Bibliográficos
Autores principales: Zhen, Xiangkai, Li, Bowen, Hu, Fen, Yan, Shufeng, Meloni, Gabriele, Li, Huiliang, Shi, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473870/
https://www.ncbi.nlm.nih.gov/pubmed/28623291
http://dx.doi.org/10.1038/s41598-017-03768-9