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Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates
We present the anticancer properties of cis, cis, trans-[Pt(IV)(NH(3))(2)Cl(2)(OA)(2)] [Pt(IV)diOA] (OA = octanoato), Pt(IV) derivative of cisplatin containing two OA units appended to the axial positions of a six-coordinate Pt(IV) center. Our results demonstrate that Pt(IV)diOA is a potent cytotoxi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473904/ https://www.ncbi.nlm.nih.gov/pubmed/28623355 http://dx.doi.org/10.1038/s41598-017-03864-w |