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H(2)S and homocysteine control a novel feedback regulation of cystathionine beta synthase and cystathionine gamma lyase in cardiomyocytes

Hydrogen sulfide (H(2)S), a cardioprotective gas, is endogenously produced from homocysteine by cystathionine beta synthase (CBS) and cystathionine gamma lyase (CSE) enzymes. However, effect of H(2)S or homocysteine on CBS and CSE expression, and cross-talk between CBS and CSE are unclear. We hypoth...

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Detalles Bibliográficos
Autores principales: Nandi, Shyam Sundar, Mishra, Paras Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473925/
https://www.ncbi.nlm.nih.gov/pubmed/28623294
http://dx.doi.org/10.1038/s41598-017-03776-9