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ADAMTS and ADAM metalloproteinases in osteoarthritis – looking beyond the ‘usual suspects’
INTRODUCTION: Matrix metalloproteinases (MMPs) and ‘aggrecanase’ a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) are well established to play key roles in osteoarthritis (OA) through degradation of extracellular matrix (ECM) type II collagen and aggrecan, and are thus potent...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders For The Osteoarthritis Research Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473942/ https://www.ncbi.nlm.nih.gov/pubmed/28216310 http://dx.doi.org/10.1016/j.joca.2017.02.791 |