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Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathway

BACKGROUND: The COP9 signalosome (CSN) is a conserved protein complex composed of 8 subunits designated CSN1-CSN8. CSN3 represents the third subunit of the CSN and maintains the integrity of the complex. CSN3 binds to the striated muscle-specific β1D integrin tail, and its subcellular localization i...

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Detalles Bibliográficos
Autores principales: Ba, Mariam A., Surina, Jeffrey, Singer, Cherie A., Valencik, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474012/
https://www.ncbi.nlm.nih.gov/pubmed/28623958
http://dx.doi.org/10.1186/s40360-017-0154-5