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Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data

BACKGROUND: The analysis of viral vector genomic integration sites is an important component in assessing the safety and efficiency of patient treatment using gene therapy. Alongside this clinical application, integration site identification is a key step in the genetic mapping of viral elements in...

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Detalles Bibliográficos
Autores principales: Kamboj, Atul, Hallwirth, Claus V., Alexander, Ian E., McCowage, Geoffrey B., Kramer, Belinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474025/
https://www.ncbi.nlm.nih.gov/pubmed/28623888
http://dx.doi.org/10.1186/s12859-017-1719-4