Next-gen sequencing identifies non-coding variation disrupting miRNA-binding sites in neurological disorders

Understanding the genetic factors underlying neurodevelopmental and neuropsychiatric disorders is a major challenge given their prevalence and potential severity for quality of life. While large-scale genomic screens have made major advances in this area, for many disorders the genetic underpinnings...

Descripción completa

Detalles Bibliográficos
Autores principales: Devanna, P, Chen, X S, Ho, J, Gajewski, D, Smith, S D, Gialluisi, A, Francks, C, Fisher, S E, Newbury, D F, Vernes, S C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474318/
https://www.ncbi.nlm.nih.gov/pubmed/28289279
http://dx.doi.org/10.1038/mp.2017.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474318/
https://www.ncbi.nlm.nih.gov/pubmed/28289279
http://dx.doi.org/10.1038/mp.2017.30

Ejemplares similares