Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy

Inflammation plays a considerable role in the progression of Duchenne Muscular Dystrophy (DMD), a severe muscle disease caused by a mutation in the dystrophin gene. We previously showed that genetic ablation of Protein Kinase C θ (PKCθ) in mdx, the mouse model of DMD, improves muscle healing and reg...

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Detalles Bibliográficos
Autores principales: Marrocco, V., Fiore, P., Benedetti, A., Pisu, S., Rizzuto, E., Musarò, A., Madaro, L., Lozanoska-Ochser, B., Bouché, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474428/
https://www.ncbi.nlm.nih.gov/pubmed/28089792
http://dx.doi.org/10.1016/j.ebiom.2017.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474428/
https://www.ncbi.nlm.nih.gov/pubmed/28089792
http://dx.doi.org/10.1016/j.ebiom.2017.01.001

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