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Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance

Increases in plasma LDL-cholesterol have unequivocally been established as a causal risk factor for atherosclerosis. Hence, strategies for lowering of LDL-cholesterol may have immediate therapeutic relevance. Here we study the role of human neutrophil peptide 1 (HNP1) in a mouse model of atheroscler...

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Detalles Bibliográficos
Autores principales: Paulin, Nicole, Döring, Yvonne, Kooijman, Sander, Blanchet, Xavier, Viola, Joana R., de Jong, Renske, Mandl, Manuela, Hendrikse, Jeffrey, Schiener, Maximilian, von Hundelshausen, Philipp, Vogt, Anja, Weber, Christian, Bdeir, Khalil, Hofmann, Susanna M., Rensen, Patrick C.N., Drechsler, Maik, Soehnlein, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474437/
https://www.ncbi.nlm.nih.gov/pubmed/28111237
http://dx.doi.org/10.1016/j.ebiom.2017.01.006