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Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes

Brown adipose tissue (BAT) represents a promising agent to ameliorate obesity and other metabolic disorders. However, the abundance of BAT decreases with age and BAT paucity is a common feature of obese subjects. As brown adipocytes and myoblasts share a common Myf5 lineage origin, elucidating the m...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Liu, Weiyi, Nie, Yaohui, Qaher, Mulan, Horton, Hannah Elizabeth, Yue, Feng, Asakura, Atsushi, Kuang, Shihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474440/
https://www.ncbi.nlm.nih.gov/pubmed/28117277
http://dx.doi.org/10.1016/j.ebiom.2017.01.015